This article delves into the challenges due to the usage of high aq. mobile phases in RPLC and offers solutions

Selecting the right HPLC column dimensions during HPLC method development

How to reduce mobile phase consumption during HPLC analysis

Impact of Triethylamine on Retention, and Peak Tailing in HPLC analysis

Understand the silanol effect and way out to minimize it in RPLC

tailing factor assymetry factor and symmtery factor as per USP and EP or Ph. Eur

measurement of plate number and resolution in HPLC analysis

This blog will help you to maximize the performance of your HPLC column

Peak tailing phenomenon, symptoms, and corrections

Hoe gradient elution can help in peak compression

The role of pH and pKa on retention of acid and base in RPLC

Use of amino column in HPLC method development

Retention of Acidic, Basic, and Neutral Compounds in Ion Pair Chromatography

Exploring the Surprising Increase in Retention Time of Protonated Bases at Low pH in RPLC

We will explore, why Acetonitrile has higher elution strength than methanol.

The role of Phenyl column in HPLC method development

what core-shell particles are, how they differ from traditional porous particles, their history, and the advantages they bring

we'll explore the unique properties of methanol and acetonitrile and discuss when and why you might prefer one over the other for HPLC

Understanding the key terms associated with QbD (Quality by Design) and AQbD (Analytical Quality by Design)

highly effective tips for column cleaning, particularly geared toward reverse-phase liquid chromatography